1. 精神错乱;疯狂;癫狂
Derangement is the state of being mentally ill and unable to think or act in a controlled way.
1. the act of disturbing the mind or body
e.g. his carelessness could have caused an ecological upset
she was unprepared for this sudden overthrow of their normal way of living
2. a state of mental disturbance and disorientation
Synonym: mental unsoundnessunbalance