1. 把…锁起妥藏
    If you lock something up in a place or container, you put or hide it there and fasten the lock.

2. 把…关入监狱（或精神病院）
    To lock someone up means to put them in prison or a secure psychiatric hospital.

3. 锁好（建筑物或汽车的）门窗
    When you lock up a building or car or lock up, you make sure that all the doors and windows are locked so that nobody can get in.

1. place in a place where something cannot be removed or someone cannot escape

    e.g. The parents locked her daughter up for the weekend
           She locked her jewels in the safe

    Synonym: lock inlock awaylockput awayshut upshut away

2. secure by locking

    e.g. lock up the house before you go on vacation