ruining the plan 破坏计划
ruining someone's reputation 毁掉某人的名誉
ruining the fun 扫兴
ruining one's health 损害健康
A: Why are you looking so upset?
A：你为什么看起来这么沮丧？
B: I feel like my mistakes are ruining everything.
B：我觉得我的错误正在毁掉一切。
1) 破坏，毁坏
2) 搞砸，使变糟
3) 败坏（名誉等）
1. 破坏；毁坏；使变糟
verb
1. To damage something so badly that it is no longer useful or good.
Synonym: destroy, spoil, damage