1. (对圣地或圣物的)亵渎,渎圣
    Sacrilege is behaviour that shows great disrespect for a holy place or object.

2. (对名人或普遍信仰的)大不敬,冒犯,无礼
    You can use sacrilege to refer to disrespect that is shown for someone who is widely admired or for a belief that is widely accepted.

1. blasphemous behavior
    the act of depriving something of its sacred character

    e.g. desecration of the Holy Sabbath

    Synonym: profanationdesecrationblasphemy